[POSTPRANDIAL ADAPTATION OF PANCREATIC SECRETION. On the 90th anniversary of the outstanding scientist and organizer of science, academician Aleksandr Mikhailovich Ugolev].

Aim Of Review: Statement of modern traditional and original view on essence and mechanisms of postprandial adaptation of pancreatic enzymes secretion is presented.

Main Points: The exosecretion of synthesized de novo and recreted pancreatic enzymes is adapted to nutrient content of the meal by means of duodenal-pancreatic stimulated and inhibition peptidergic mechanisms, generalized and selected-induced enzyme-substrate complexes of duodenal chyme. The managed module secreted-transported pancreatic system is important as a normal criterion in urgent adaptation.

[Types of digestion in breast feeding: returning to the problem].

During the breast feeding the hydrolysis of breast milk nutrients in natural conditions provides by milk enzymes, digestive gland secrets and intestinal epitheliocyte as autolytic induced digestion with following including and development of auto-digestion in hydrolysis of milk lipids and proteins. Milk lactose is hydrolyzed as a type of auto-intestinal digestion. Breast glands release enzymes according to a year lactation dynamics.

[DIGESTION IN BREAST FEEDING AS NATURAL TECHNOLOGY].

During the breast feeding the hydrolysis of breast milk nutrients in natural conditions provides by milk enzymes, digestive gland secrets and intestinal epitheliocyte as autolytic induced digestion with following including and development of auto-digestion in hydrolysis of milk lipids and proteins. Milk lactose hydrolyses as a type of auto-intestinal digestion. Breast glands release enzymes according to a year lactation dynamics.

[The problem of autolytic digestion at amniotropic and lactotropic feeding].

The review presented the results of the author, his co-workers and investigators of other laboratories about types of feeding (histotropic, hemotropic, amniotropic, lactotropic, definitive) and digestion (autolytic, native) of a fetus and an infant. The study was based on analysis of enzymes that provided hydrolysis of amniotic fluid and breast milk. The data about probable technology of abovementioned types of digestion in earlier stages of individual human advance and opportunity of hydrolase recretor origin in amniotic fluid and breast milk are shown.

[The transport component of the secretory activity of pancreas].

The transport processes take place on the all stages of pancreatic secretion. The article highlighted the multi-parametric regulated exosecret transport through the duct system of the pancreas. The system has valves and micro-reservoirs of secret.