Effects of bromocriptine administration to pregnant rabbits upon fetal lung maturation.

If endogenous prolactin secretion is important in normal development of fetal lung surfactant, the inhibition of its secretion should be associated with delayed maturation of fetal lung. We therefore studied the effect of bromoergocriptine administration to pregnant rabbits upon lecithin content of fetal lung washes. The does were treated since the 27th day of gestation with either Mesilate of 2-Bromo-alpha-ergocriptine (C32H40BrN5O5, CH3SO3H) (Bromocriptine) (Parlodel, Sandoz) (1 mg/kg/day) or solvent twice daily until delivery.

Estriol serum levels, neonatal vitality and stromal villous edema in diabetic pregnancies.

Estriol serum levels, neonatal vitality and stromal villous edema were studied in diabetic pregnancies. The average serum estriol levels in diabetic patients whose placentas had villous edema was 26.45 +/- 9.