Vascular Neurologists as Directors of Stroke Centers in the United States.

Background And Purpose: Hospital certification as primary and comprehensive stroke center is associated with improvement in care. We aimed to characterize the leadership at stroke centers nationwide to determine the proportion led by vascular neurologists, a board-recognized subspecialty focusing on stroke care.

Methods: We identified hospitals in the United States holding primary and comprehensive stroke center designation as of September 2013.

Imaging of occlusive thrombi in acute ischemic stroke.

Thrombi, or clots, often occlude proximal segments of the cerebral arterial circulation in acute ischemic stroke. Thromboembolic occlusion or thrombi superimposed on atherosclerotic plaque are the principal focus of acute stroke therapies such as thrombolysis or thrombectomy. We review the imaging characteristics of thrombi on multimodal computed tomography and magnetic resonance imaging, angiography, and ultrasonography, summarizing recent studies that facilitate therapeutic decision-making from these noninvasive studies.

[Growth peculiarities of commensal Escherichia coli isolates from the gut microflora in Crohn's disease patients].

Verhulst's logistic differential equation, popular in mathematical ecology, is used in modeling of population growth, neural networks, statistics, reaction models, Fermi distribution, modeling of tumor growth, etc. We used this function to characterize growth of commensal Escherichia coli isolates from gut microflora in Crohn's disease patients. The results of our investigations show differences in growth parameters of commensal E.

Image coregistration: quantitative processing framework for the assessment of brain lesions.

The quantitative, multiparametric assessment of brain lesions requires coregistering different parameters derived from MRI sequences. This will be followed by analysis of the voxel values of the ROI within the sequences and calculated parametric maps, and deriving multiparametric models to classify imaging data. There is a need for an intuitive, automated quantitative processing framework that is generalized and adaptable to different clinical and research questions.

[New Mn-chelates are radioprotectors and antioxidants for cells in vitro].

Earlier we have synthesized new Mn-chelates (Mn-compexes of ethyl ethers of salicyliden-D, L-tyrosine, -gamma-amino butyric acid and -D, L-tryptophan) bearing several free functional groups. The radioprotective and antioxidant activity of these compounds were tested on the secondary cultures of chick embryo cells. To this end the cells in vitro were gamma-irradiated with 60Co at the doses 40 and 60 Gy or treated with H2O2 at the concentration 3 mmol/l, the new Mn-chelates were added into the cultures, and the number of survived cells was determined in 24 hours.