[Risk factors of atherosclerosis in young people].

Factor analysis was used to study an association of risk factors of atherosclerosis (AS) in student during their study. These factors were shown to be rather evident just at the age of 17-22 years. The correlation matrixes in male and female students are described by a mixed number of factors and the factors differ themselves in the internal structure, magnitude, and correlation signs.

[Using biologic markers for evaluation of environmental pollution with metals].

Contemporary state of analytic basis enables to use human biologic materials adequately reflecting present ecologic situation for social hygienic monitoring of environmental pollution with heavy metals. To conduct biologic monitoring, regional databases on background metals content of human biologic materials are required. Regional data on elements contents of human body helps precise evaluation of health risk in exposure to environmental hazards.

[Hygienic evaluation of health risk for Ufa city residents under exposure to heavy metals].

The article deals with results of evaluated metals intake by residents of Ufa - major industrial city. Findings are that in absence of occupational exposure to heavy metal salts human health becomes more vulnerable to ecologic influence. Main sources of heavy metals intake by humans are foods providing over 90% of daily dose of the metals.

[Nonsteroidal anti-inflammatory drugs. Declaration I. A study of interrelation "structure--the effectiveness of anti-inflammatory action"].

Using the computer system SARD-21 (Structure Activity Relationship & Design) the structural features typical for high- and low- effective nonsteroid anti-inflammatory drugs (NSAIDs) were analyzed. This information has been used for the model for prediction of anti-inflammatory effectiveness of medicines with 76% and 81% level of recognition by two methods. New data can be used for creating new highly effective NSAIDs, and for increasing effectiveness of already known components.

Overexpression of AtCpNifS enhances selenium tolerance and accumulation in Arabidopsis.

Selenium (Se) is an essential element for many organisms but is toxic at higher levels. CpNifS is a chloroplastic NifS-like protein in Arabidopsis (Arabidopsis thaliana) that can catalyze the conversion of cysteine into alanine and elemental sulfur (S0) and of selenocysteine into alanine and elemental Se (Se0). We overexpressed CpNifS to investigate the effects on Se metabolism in plants.