Pathogenic variants in , , and cause primary ciliary dyskinesia with a defective C1d projection of the central apparatus.

Background: Primary ciliary dyskinesia is a rare genetic disorder caused by insufficient mucociliary clearance leading to chronic airway infections. The diagnostic guideline of the European Respiratory Society primarily recommends an evaluation of the clinical history ( by the PICADAR prediction tool), nasal nitric oxide production rate measurements, high-speed videomicroscopy analysis of ciliary beating and an assessment of ciliary axonemes transmission electron microscopy. Genetic testing can be implemented as a last step.

Evaluation of direct point dose estimation based on the distribution of the size-specific dose estimate.

The aim of this study was to evaluate the point doses using a distribution of the size-specific dose estimate (SSDE) from axial CT images of in-house phantoms having diameters from 8 to 40 cm. In-house phantoms made of polyester-resin (PESR) mixed with methyl ethyl ketone peroxide (MEKP) were used. The phantoms were built with different diameter sizes of 8, 16, 24, 32, and 40 cm.

A Practical Method for Slice Spacing Measurement Using the American Association of Physicists in Medicine Computed Tomography Performance Phantom.

Background: The slice spacing has a crucial role in the accuracy of computed tomography (CT) images in sagittal and coronal planes. However, there is no practical method for measuring the accuracy of the slice spacing.

Purpose: This study proposes a novel method to automatically measure the slice spacing using the American Association of Physicists in Medicine (AAPM) CT performance phantom.

A novel method for developing contrast-detail curves from clinical patient images based on statistical low-contrast detectability.

. To develop a method to extract statistical low-contrast detectability (LCD) and contrast-detail (C-D) curves from clinical patient images..