[Effect of nitrofuran derivatives on the oxygen consumption by rat liver mitochondria].

Utilization of oxygen in rat liver mitochondria was studied using two nitrofuran derivatives 5-nitro-2-furaldehyde semicarbazone (furacin) and soluble derivative of nitrofuran--M-106-P. The substances at 10(-3) M concentration increased O2 consumption in mitochondria with simultaneous decrease in the respiratory control. After blocking of respiration with KCN, antimycine, rhothenone, the nitrofurans stimulated O2 consumption in mitochondria up to 30% as compared with controls.

[Comparative study of the effect of nonionic detergents as inhibitors of respiration of tumor ascites cells].

The action of derivatives of polyoxyethylene oxide (triton X-100, triton X-305, tween 21, tween 40, tween 60, and tween 80) on respiration of Ehrlich's tumor and rats ovarium tumor cells involved inhibition of the cells respiration due to alteration of commonly uncorrelated with the distribution of detergents between the cell and the extracellular milieu.