The results of analysis of the efficiency of a new hemostatic napkin containing iron salts for the local arrest of hemorrhage in patients undergoing tonsillectomy. The application of these materials was shown to effectively stop the hemorrhage and reduce the risk of its relapse.
View Article and Find Full Text PDFSpecific activity of a new hemostatic drug thrombocol was studied in experiments. Laboratory rabbits were used for management of experimental capillary-parenchymatous hemorrhage. The action of thrombocol was compared with hemostatic effect of other drugs: carbocol, combutek-2, super-4 (USA), collastipt (Germany), collagen sponge (Germany).
View Article and Find Full Text PDFThe paper summarizes the data available on utilization of drugs diverse by chemical structure and mechanism of action for local arrest of capillary-parenchymal hemorrhages. Basic drugs in the field are listed with indication of their drawbacks. Further efforts should be directed to management of these side effects.
View Article and Find Full Text PDFIn rabbits with experimental hypocoagulation induced by phenylin, the use of a new dosage form of vitamin K1 for intravenous injections in does of 1 and 5 mg/kg led, in contrast to vicasol in a dose of 0.4 mg/kg, to an increase of the prothrombin index after 2 hours and to its complete normalization after 4 hours. Intravenous injection of vitamin K1 into intact animals did not entail any changes in the activated partial thromboplastin time, thrombin and prothrombin time, in the content of fibrinogen and products of its biotransformation, antithrombin III activity, and fibrinolytic activity or in the count of platelets and their aggregation capacity.
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