Publications by authors named "G G A Hutchins"
Background And Purpose: There are multiple MRI perfusion techniques, with limited available literature comparing these techniques in the grading of pediatric brain tumors. For efficiency and limiting scan time, ideally only one MRI perfusion technique can be used in initial imaging. We compared DSC, DCE, and IVIM along with ADC from DWI for differentiating high versus low grade pediatric brain tumors.
View Article and Find Full Text PDFBackground: Incarcerated individuals in carceral facilities demonstrate an elevated prevalence of chronic disease conditions which are likely to persist post-release. Healthcare providers may not be trained on how exposure to incarceration may influence patient health outcomes and patient-provider communication.
Objective: To examine the self-perceived preparedness of healthcare providers to interview patients regarding history of incarceration and the potential related health consequences.
Sinonasal squamous cell carcinomas (SNSCCs) are uncommon and they are associated with adverse prognosis. HPV-associated SNSCCs and fusion-driven SNSCCs are particularly rare. A case of an HPV-associated SNSCC with a FGFR3::TACC3 fusion is thus presented; a brief review of the pertinent literature is also provided.
View Article and Find Full Text PDFArticle Synopsis
- High densities of CD3 and CD8 T-cells in colorectal cancer are linked to better patient prognosis, but their effectiveness in predicting chemotherapy benefits remains unclear.
- A study analyzed tumor tissue from 868 colorectal cancer patients and found that those with high-risk CD3/CD8 cell densities had recurrence rates twice as high as low-risk patients, consistently observed in both training and validation sets.
- The findings suggest that while high-risk patients experience more recurrences, chemotherapy provides similar proportional benefits across both high- and low-risk groups, leading to updated treatment recommendations based on the CD3/CD8 cell density scores.
Purpose: Survivors of surgically managed prostate cancer may experience urinary incontinence and erectile dysfunction. Our aim was to determine if Ga-prostate-specific membrane antigen-11 positron emission tomography CT (PSMA-PET) in addition to multiparametric (mp) MRI scans improved surgical decision-making for nonnerve-sparing or nerve-sparing approach.
Materials And Methods: We prospectively enrolled 50 patients at risk for extraprostatic extension (EPE) who were scheduled for prostatectomy.