Publications by authors named "G Fucci"
Article Synopsis
- - The study sought to determine if the enzyme PDE5, important for sexual and cardiovascular health, can be detected and measured in human serum, particularly in relation to prostate cancer (PCa).
- - Blood samples from various subjects, including those with PCa and benign prostatic hypertrophy (BPH), showed detectable PDE5 levels, with significant differences observed between PCa patients and controls.
- - The results suggest that serum PDE5 levels can serve as a potential predictor for PCa, with a noteworthy sensitivity and specificity; however, more research is needed to fully understand its clinical significance.
We report the first data on 25-hydroxyvitamin D plasma levels in natural populations of three species of land iguana endemic to the Galápagos Islands (, , and ). The pigment is present throughout the whole body in the skin of and . On the contrary, pigment is not present in the skin of an extended part of the body in .
View Article and Find Full Text PDFVitamin C has been shown to play a significant role in suppressing progression of leukemia through epigenetic mechanisms. We aimed to study the role of vitamin C in acute myeloid leukemia (AML) biology and clinical course. To this purpose, the plasma levels of vitamin C at diagnosis in 62 patients with AML (including 5 cases with acute promyelocytic leukemia, APL),7 with myelodysplastic syndrome (MDS), and in 15 healthy donors (HDs) were studied.
View Article and Find Full Text PDFAcademic centers utilize sequential clinical and neuroimaging assessments, including morphometric ratios, to obtain an unequivocal diagnosis of the non-synucleinopathic forms of Parkinsonism, such as progressive supranuclear palsy (PSP), however, a 1-2 year follow-up is required. The on-going long-lasting trials using anti-tau antibodies for PSP patients might therefore be biased by the incorrect enrollment of Parkinson's disease (PD) patients manifesting early axial signs. This perspective study aimed at achieving two major goals: first, to summarize the established biomarker candidates found in cerebrospinal fluid (CSF) in probable PSP patients, including low p-tau and altered neurofilaments.
View Article and Find Full Text PDFBackground: Epidemiological studies have proved that tomato consumption is associated with a lower risk of developing several diseases (for example, certain types of cancers, cardiovascular diseases, macular degeneration, age-related eye disease). Many micronutrients and bioactive compounds are mainly present in peel and seeds and are lost during the processing into sauce, purée, paste and juice.
Results: The addition of lyophilized and powdered tomato pomace enhances the properties of purée.