Publications by authors named "G Fritsch"
Extracorporeal membrane oxygenation (ECMO) provides critical support for patients with severe cardiopulmonary dysfunction. Unfractionated heparin (UFH) is used for anticoagulation to maintain circuit patency and avoid thrombotic complications, but it increases the risk of bleeding. Extracellular vesicles (EVs), nano-sized subcellular spheres with potential pro-coagulant properties, are released during cellular stress and may serve as potential targets for monitoring anticoagulation, particularly in thromboinflammation.
View Article and Find Full Text PDFOptimizing the regeneration process of surgically created anastomoses (blood vessels, intestines, nerves) is an important topic in surgical research. One of the most interesting parameter groups is related to the biomechanical properties of the anastomoses. Depending on the regeneration process and its influencing factors, tensile strength and other biomechanical features may change during the healing process.
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- Evolutionary changes in RNA translation rates and new genes, including small open reading frames, play a key role in the development of innovations in primates and rodents.
- This study examined the hearts of four primate species and two rodent species using advanced ribosome and transcriptomic profiling techniques, focusing on adult heart tissues and stem cell-derived heart cells.
- Findings revealed rapid evolution in the translation efficiency of mitochondrial complexes and identified numerous unique genomic features related to primate heart evolution, highlighting mechanisms that influence cardiac development and potential disease.
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- Elephants display unique lateralization in their trunk behaviors, which is influenced by the organization of their mouth and facial structures.
- The study reveals that elephants have a narrow lower jaw that is elongated, with their lip vibrissae becoming progressively longer and asymmetrically worn due to feeding behaviors.
- Unlike ancestral mammals, elephants have undergone significant anatomical changes, such as upper lip fusion with the trunk and a shift towards lateral microvibrissae, adapting their feeding methods from traditional oral apprehension to trunk-based feeding.
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- Billfish rostra serve multiple roles, but are crucial for feeding in some species; recent studies link rostral micro-teeth variation to different feeding behaviors in striped marlin and sailfish.
- This study introduces the rostral micro-tooth morphology of blue marlin, highlighting their feeding behavior remains undocumented in the wild, despite previous video analyses of other billfish revealing striking patterns.
- Findings show blue marlin have longer intact micro-teeth but a higher incidence of broken teeth compared to striped marlin and sailfish, suggesting their rostrum functions in high-speed dashes targeting larger prey instead of precision strikes.