Publications by authors named "G Fries"
Article Synopsis
- Childhood maltreatment is linked to changes in epigenetics and brain-derived neurotrophic factor (BDNF), which play a role in psychiatric conditions like bipolar disorder (BD), though specific mechanisms are still unclear.
- The study involved 36 BD patients and 46 healthy controls, using the Childhood Trauma Questionnaire (CTQ) to evaluate the history of maltreatment and various biological markers related to epigenetics and BDNF.
- Findings indicate that emotional abuse is the main type of childhood maltreatment affecting epigenetic markers in BD, but it is suggested that these effects are cumulative and may interact with other factors influencing BD, rather than being a direct cause of the disorder.
Bipolar disorder (BD) has been linked to accelerated aging processes, with many studies suggesting that drugs used to treat BD may modulate pathways related to aging. This systematic review aimed to determine whether FDA-approved pharmacotherapies for BD have reported effects on aging biomarkers across clinical and preclinical studies. We conducted searches in PubMed and PsychINFO and followed PRISMA guidelines.
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- The study aimed to evaluate a new aiming compression device (ACD) for inserting screws into non-fractured navicular bones (NB) using 10 adult horse cadaver limbs.
- The procedure, conducted under radiographic guidance, showed an average time of 33.5 minutes, with screw placement assessed as excellent in 9 out of 10 bones, and only one case rated poorly.
- The findings suggest that the technique effectively allows for screw placement without damaging surrounding bone structures, highlighting its potential for future clinical applications in NB fracture repair.