Publications by authors named "G Fraedrich"

Background: The optimal antithrombotic (antiplatelet or anticoagulant) treatment of patients undergoing extracranial carotid artery interventions is a subject of debate. The aim of this multidisciplinary document was to critically review the recommendations of current guidelines, taking into consideration the results of recently published studies.

Methods: The various antithrombotic strategies reported were evaluated for asymptomatic and symptomatic patients undergoing extracranial carotid artery interventions (endarterectomy, transfemoral carotid artery stenting [CAS] or transcarotid artery revascularization [TCAR]).

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Article Synopsis
  • Current guidelines advise against screening for asymptomatic carotid artery stenosis (AsxCS) due to the risk of unnecessary interventions, unlike the strong recommendation for abdominal aortic aneurysm screening.
  • A literature analysis reveals that patients with AsxCS are at a high risk for future cardiovascular issues, yet universal screening is not advisable.
  • Selective screening for high-risk individuals could be beneficial, focusing on risk factor management and medical therapy to prevent future cardiovascular events rather than identifying candidates for surgery.
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Background: The optimal treatment for patients with asymptomatic carotid artery stenosis is under debate. Since best medical treatment (BMT) has improved over time, the benefit of carotid endarterectomy (CEA) or carotid artery stenting (CAS) is unclear. Randomised data comparing the effect of CEA and CAS versus BMT alone are absent.

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