Publications by authors named "G Filosa"

Article Synopsis
  • Lung cancer (both non-small cell and small cell types) is currently treated with a mix of chemo- and immunotherapy, but effective biomarkers for predicting patient responses are needed.
  • The study focuses on the cGAS-STING pathway in peripheral blood mononuclear cells (PBMCs) to identify treatment responses in lung cancer patients, revealing that better responders had significantly higher levels of STING and CXCL10.
  • Results suggest that activating the cGAS-STING signaling in PBMCs could serve as a novel predictor for immunotherapy response, with higher levels indicating better treatment outcomes and enhanced anti-tumor immune activity.
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Patients with early stage cutaneous T cell lymphoma (CTCL) usually have a benign and chronic disease course, characterized by temporally response to conventional skin directed therapies and intrinsic possibility to evolve. Using the combination of psoralen plus ultraviolet A irradiation (PUVA) and low-dose interferon-α (INF), the principal treatment goal is to keep confined the disease to the skin, preventing disease progression. Among 87 patients with early stage IA to IIA MF treated with low-dose IFN-α2b and PUVA in our center, complete remission (CR) were reported in 70 patients (80.

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The behaviour of high oleic sunflower oil in deep frying process of purple potato has been evaluated simulating a fast food cooking process. This oil was used for 8h/day for 6 days, filling up from the 2nd day. A discontinuous and prolonged procedure was tested.

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Background: Clinical and pathologic criteria to distinguish drug-induced subacute lupus erythematosus (DI-SCLE) from idiopathic (I-SCLE) are controversial.

Objective: The aim of the survey was a retrospective analysis of a consistent number of iatrogenous and idiopathic SCLE cases, by means of clinical and histopathologic investigation.

Methods: Eleven European university dermatology units collected all diagnosed cases from January 2000 to December 2016.

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