Publications by authors named "G Favata"
Article Synopsis
- Catheter-related bloodstream infections (CRBSIs) pose significant health risks and additional costs for ICU patients, prompting a study to evaluate their prevalence in accordance with international guidelines for vascular line management.
- The study, conducted in an Italian ICU over five years, involved 1240 patients, revealing a total of 9 diagnosed CRBSIs with varying infection rates depending on catheter types.
- Results indicated that CRBSIs are associated with factors like nursing activity levels and specific ICU admission reasons, and implementing recommended care protocols incurred a cost of EUR 130.00 per patient.
Identification of IL-17F/frequent exacerbator endotype in asthma.
J Allergy Clin Immunol
August 2017
Background: Severe asthma might be associated with overexpression of T17 cytokines, which induce neutrophil recruitment via neutrophil-mobilizing cytokines in airways.
Objective: To study IL-17-related cytokines in nasal/bronchial biopsies from controls and mild asthmatics (MAs) to severe asthmatics (SAs) in relation to exacerbation rate.
Methods: Inflammatory cells and IL-17A, IL-17F, IL-21, IL-22, and IL-23 cells were examined by immunohistochemistry in cryostat sections of bronchial/nasal biopsies obtained from 33 SAs (21 frequent exacerbators [FEs]), 31 MAs (3 FEs), and 14 controls.
Severe asthma (SA) is associated with neutrophil recruitment and T helper (TH )17 chemokine overexpression in bronchial biopsies. We aimed to evaluate IL-17A and IL-17F expression in nasal/bronchial lamina propria of atopic mild-to-severe asthmatics and controls in relation to neutrophilia and asthma exacerbations. Cryostat sections of nasal/bronchial biopsies obtained from 14 SA and 14 mild asthma (MA) stable atopic patients with rhinitis, and seven healthy controls were analyzed by immunohistochemistry for neutrophils, IL-17A and IL-17F expression.
View Article and Find Full Text PDFObjective: This study explored the effectiveness of a psychoeducational family intervention for schizophrenia on patients' clinical status and disability and relatives' burden and perceived support.
Methods: The study has been carried out in 17 mental health centres. In each of them, 2 professionals were trained in a psychoeducational intervention and applied it for six months with families of users with schizophrenia.
Aims: This study aims to explore: a) the feasibility of psycho-educational interventions for families of users with schizophrenia in clinical practice by trained staff; b) the benefits and problems encountered by professionals in the use of these interventions.
Methods: 46 professionals from 23 Italian Mental Health Services (MHS) attended at a three-module training course in psycho-educational interventions and four supervisions in the subsequent year. Following the course, participants provided the intervention to families of users with schizophrenia.