Publications by authors named "G Farante"

Purpose: To present an overview of the management of male patients with Ductal Carcinoma In Situ of the breast (male DCIS).

Methods: We retrospectively studied all male patients with a diagnosis of pure DCIS from January 1999 to December 2018: 20 patients were identified in our cancer referral center. We collected data regarding clinical presentation, age of onset, radiological features, receptor status of the neoplasm, histological type, and the follow-up of those patients.

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Article Synopsis
  • The study aimed to create a tool to predict if low-grade breast cancer (DCIS) would turn into a more serious form (invasive carcinoma) after surgery.
  • Researchers looked at data from 3100 breast biopsies and focused on 295 cases of low-grade DCIS.
  • They found that factors like age and the size of any remaining lesions after the biopsy could help predict the risk of cancer worsening, and they developed a simple chart to assist doctors in assessing this risk.
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Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer. It accounts for 25% of all breast cancers diagnosed, as a result of the expansion of breast cancer screening and is associated with a high survival rate. DCIS is particularly clinically challenging, due to its heterogeneous pathological and biological traits and its management is continually evolving towards more personalized and less aggressive therapies.

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Objective: The aim of this study was to compare robotic mastectomy with open classical technique outcomes in breast cancer patients.

Summary Background Data: As the use of robotic nipple sparing mastectomy continues to rise, improved understanding of the surgical, oncologic, and quality of life outcomes is imperative for appropriate patient selection as well as to better understand indications, limits, advantages, and dangers.

Methods: In a phase III, open label, single-center, randomized controlled trial involving 80 women with breast cancer (69) or with BRCA mutation (11), we compared the outcome of robotic and open nipple sparing mastectomy.

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