Publications by authors named "G Fantoni"
Most cases of invasive meningococcal disease (IMD) in Europe are caused by isolates of the serogroups B, C, W, and Y. We aimed to explore cases caused by other unusual serogroups. We retrospectively screened IMD cases in the databases of the National Reference Center for Meningococci and in France between 2014 and 2023.
View Article and Find Full Text PDFSomaScan is an aptamer-based proteomics assay designed for the simultaneous measurement of thousands of human proteins with a broad range of endogenous concentrations. The 7K SomaScan assay has recently been expanded into the new 11K version. Following up on our previous assessment of the 7K assay, here, we expand our work on technical replicates from donors enrolled in the Baltimore Longitudinal Study of Aging.
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- * Antibody titer is currently the main way to evaluate how well bacterial vaccines work, but it doesn’t capture all the immune functions provided by antibodies.
- * Functional assays, like serum bactericidal and opsonophagocytosis assays, are necessary for a complete understanding of antibody activity; however, standardizing these tests is challenging and further improvements are needed for broader use in vaccine assessment.
Purpose: Uncertainty and complexity have increased in recent decades, posing new challenges to humanitarian organisations. This study investigates whether using standard terminology in Human Resource Management processes can support the Humanitarian supply chain in attracting and maintaining highly skilled operators.
Methodology: We exploit text mining to compare job vacancies on ReliefWeb, the reference platform for humanitarian job seekers, and ESCO, the European Classification of Skills, Competencies, and Occupations.
Immunological health has been challenging to characterize but could be defined as the absence of immune pathology. While shared features of some immune diseases and the concept of immunologic resilience based on age-independent adaptation to antigenic stimulation have been developed, general metrics of immune health and its utility for assessing clinically healthy individuals remain ill defined. Here we integrated transcriptomics, serum protein, peripheral immune cell frequency and clinical data from 228 patients with 22 monogenic conditions impacting key immunological pathways together with 42 age- and sex-matched healthy controls.
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