Publications by authors named "G F Villa"

Background: Growth Differentiation Factor 15 (GDF15) has been described as influencing skeletal physiology. Nevertheless, no systematic appraisal of the effect of GDF15 on skeletal muscle tissues has been developed to the present day.

Objective: The aim of the present work was to review the evidence on the topic.

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Vertical jump height from a countermovement jump is a widespread metric to assess the lower limb functionality. Motion capture systems and force platforms are considered gold standards to estimate vertical jump height; however, their use in ecological settings is limited. This study aimed to evaluate the feasibility of low-sampling-rate inertial measurement units as an alternative to the gold standard systems.

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: Respiratory tract infections (RTIs) are a leading cause of pediatric emergency department (PED) visits, especially in children under five. These infections are primarily viral, complicating diagnosis and management. This study assesses the impact of point-of-care (POC) rapid diagnostic tests for respiratory viruses on clinical and economic outcomes in a PED setting.

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Article Synopsis
  • Glioblastomas are aggressive brain tumors that resist treatment and utilize neuron-tumor connections to promote their growth, with cholinergic neurons playing a key role in this invasion.
  • The study utilized rabies viruses for retrograde tracing to reveal how glioblastomas integrate into brain circuits, showing that radiotherapy can enhance neuron-tumor connectivity, complicating treatment efforts.
  • By disrupting neuron-tumor connections, researchers discovered a potential therapeutic approach that could halt glioblastoma progression, emphasizing the need to target these synapses for better treatment outcomes.
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