[Psychophysiological development of two generations of female rats chronically exposed to gamma-irradiation during pregnancy in the total dose of 1 Gy and its modification by melanin].

The purpose of the work was to study the embryotoxic action of chronic gamma-irradiation of pregnant female rats (F0) during the first 10 days of pregnancy in the total dose of 1 Gy (mean dose rate of 5.31 mGy/hour) on psychophysiological development of posterity of the first (F1) and the second (F2) generations and its modification by natural pigment melanin (peroral 10 mg/kg once per day during the irradiation). 54 pregnant female Wistar rats were the objects of research were their 180 descendants of the first generation and about 400 descendants of the second generation of maternal and of paternal lines.

[Consequences for posterity of two generations of an irradiation pregnant from females rats Wistar in small doses during a bookmark of reproduction system of fetuses development of posterity of the second generation and it reproduction function].

With the purpose of study of consequences for development and reproduction functions of posterity of the second generation from females rats Wistar of a total unitary gamma-irradiation in dozes 0.25; 0.5 and 1 Gy (capacity of a doze 0.

[The influence of the exogenous melanin on the development of the second generation of the female Wistar rats exposed during the critical period of the pegnancy at the nonsterilizing doses of different rate means].

The purpose of this study was to estimate the radio-protective activity of melanin for the reproductive status of Wistar rats. Wistar rats were exposed in utero either to the single gamma-irradiation on the tenth day of embryogenesis with the dose of 1 Gy or to the chronic gamma-irradiation with the total dose of 1 Gy during the first 10 days of embryogenesis. Such things like the ability of the rats to conceive, the embryogeny and early postnatal ontogeny of rat's posterity were studied.

[The influence of exogenous melanin on the development of female Wistar rats' posterity of first generation exposed to low doses at different dose rates during embryogenesis].

To research a radio-protective effect of melanin on the reproductive system during its creation the development of first generation posterity (900 descendants) of 125 pubertal female Wistar rats was examined after the single gamma-irradiation with a dose of 1 Gy (mean dose rate of 0.03 mGy/h), which they have been exposed to on the day ten of pregnancy, and the chronic gamma-irradiation with a total dose of 1 Gy (mean dose rate of 5.31 mGy/h) which they have been being exposed to during the first 10 days of pregnancy.

[Reaction of posterity of two generations after exposure of pregnant Wistar rats to low dose irradiation during the period of fetus formation. Development of the first generation posterity].

Whole-body single exposure of female Wistar rats to 0.25, 0.5 and 1 Gy of gamma-rays (dose rate of 0.