Publications by authors named "G F Maĭorova"

The data on the examination of 5139 serum samples, obtained from 3358 blood donors and 1781 somatic patients, for the presence of HCV, HBV and HDV markers. Antibodies (Ab) to HCV were detected, on the average, in 1.56% of the examined blood donors (207 persons).

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The immunogenicity, immunological and epidemiological effectiveness of the subcutaneous, enteral and combined immunizations of the workers at a steel plant with staphylococcal toxoid has been studied. The subcutaneous injection of the adsorbed toxoid in a dose of 0.2 ml by means of the jet injector, model, was accompanied by moderate reactogenicity (the frequency of local reactions was 26.

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Delayed hypersensitivity (DH) was induced in rabbits by introducing killed St. aureus culture in incomplete Freund's adjuvant. 7 days later the animals were infected intradermally with alpha-toxigenic and leukocidin-active St.

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By double immunization of 72 persons and single reimmunization of 38 persons per os with tablets containing 100 BU of purified concentrated staphylococcus toxoid (PCST) it was revealed that this immunization was harmless and the immunological response was adequate. The tablets were intended for application through the oral mucosa (oral) or the intestinal tract (enteral); the immunological response depended on the dose of the preparation and the scheme of administration. A high sensitization of healthy persons examined to staphylococcus was found.

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