Publications by authors named "G F Kersten"
Article Synopsis
- Medical students are under a lot of stress and mental health issues, and this study looked into how self-determination theory (SDT) could boost their motivation and decrease stress during learning.
- The study involved a week-long psychiatry course where one group of students experienced a new teaching style focused on autonomy and positive reinforcement, compared to a traditional approach.
- Results showed that the innovative method increased intrinsic motivation and perceived autonomy while reducing stress, though it also led to lower exam scores due to the lack of critical feedback.
Article Synopsis
- Doctors and psychologists in psychiatric hospitals start teaching right away, even if they haven't learned how to teach properly.
- A survey was sent out to gather opinions from teachers at medical schools in German-speaking countries about the skills and training they need for teaching.
- Most respondents agreed that learning how to teach well is very important, showing strong interest in practical teaching methods like bedside teaching and improving communication skills.
To develop cryopreservation methods for cell-based medicinal products it is important to understand osmotic responses of cells upon immersion into solutions with cryoprotective agents (CPAs) and during freezing. The aim of this study was to assess the osmotic response of T cells by using flow imaging microscopy (FIM) as a novel cell-sizing technique, and to corroborate the findings with electrical impedance measurements conducted on a Coulter counter. Jurkat cells were used as a potential model cell line for primary T cells.
View Article and Find Full Text PDFVaccines undergo stringent batch-release testing, most often including in-vivo assays for potency. For combination vaccines, such as diphtheria-tetanus-pertussis (DTaP), chemical modification induced by formaldehyde inactivation, as well as adsorption to aluminum-based adjuvants, complicates antigen-specific in-vitro analysis. Here, a mass spectrometric method was developed that allows the identification and quantitation of DTaP antigens in a combination vaccine.
View Article and Find Full Text PDFThe aim of this study was to demonstrate the strength of combining immunochemical and biophysical analysis tools for assessing the quality of Sabin inactivated poliovirus vaccine (Sabin-IPV) bulk products. We assessed Sabin-IPV serotypes 1, 2 and 3 from six different manufacturers and evaluated their comparability through biosensor analysis and biophysical characterization methods, including tryptophan fluorescence and asymmetrical flow field-flow fractionation - multi-angle light scattering analysis. These methods enabled us to assess antigenic as well as conformational and structural integrity profiles, respectively.
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