Epigenetic regulation of the shape and position of the auricle in the rat.

We hypothesized that epigenetic (non-genomic) factors, related to muscular function, significantly regulate the shape and position of the auricular cartilage. We tested this experimentally by doing unilateral partial and total facial neurectomies, auricular myectomies, and ear rotations with skin excisions in rats. The neurectomies produced muscle atrophy, abolished the horizontal scaphoid ridging, and produced characteristic changes in the auricular shape.

Aggressive histological features of keratoacanthoma.

Thirty-nine keratoacanthomas from 35 patients have been studied, six of which showed perineural, and one vascular, invasion. Thus far, their aggressive histological behavior has not been paralleled by a similar clinical course. However, continued close follow-up is essential.

Gasoline and flammable and nonflammable clothing studies.

Studies were conducted on mannequins using gasoline and flammable and nonflammable children's clothing. The results indicate that the flame-resistant standards currently required by law for children's sleepweare lead to much less severe burns.