Publications by authors named "G F Bomfim"
Copaifera sp. is a native tree in the Amazon region. Copaiba oleoresin has components such as sesquiterpenes, which have anti-inflammatory and antioxidant potential.
View Article and Find Full Text PDFCorrection: Patias et al. Effect of Liposomal (Alb.) March Extract in the Treatment of Obesity Induced by High-Calorie Diet. 2024, , 535.
Biology (Basel)
October 2024
Article Synopsis
- The original publication discusses key findings or concepts that are significant to the topic.
- It outlines the methodology used in the study or research conducted, providing insight into how conclusions were drawn.
- The text also highlights the implications of these findings, suggesting their relevance to current knowledge or future research.
(), popularly known as "almacega" or "white pitch", is widely used in folk medicine due to its antioxidant, anti-inflammatory and healing properties, attributed to its richness in flavonoids and terpenes. Therefore, this study aimed to evaluate the effects of treatment for 28 days with liposomes containing leaf extract in obese animals. Male Wistar rats, subjected to a hypercaloric diet for 8 weeks to induce obesity (hypercaloric chow and water enriched with 30% sucrose, ad libitum), were treated with the plant formulation (1 mg kgday, via gavage) for 28 days.
View Article and Find Full Text PDFStudy of Liposomes Containing Extract from the Leaves of (Aubl.) March in Animals Submitted to a Mutagenic Model Induced by Cyclophosphamide.
Biology (Basel)
September 2024
Article Synopsis
- * Mice were pre-treated with liposomes containing the extract for 14 days before receiving a single dose of CPA, followed by various biochemical and histopathological analyses to assess the effects on oxidative stress and DNA damage.
- * Results indicated that the liposomal extract had an antimutagenic effect, enhanced antioxidant enzyme levels, and showed potential kidney and liver protective benefits, suggesting that the flavonoids in the plant extract could offer a promising method for cancer chemoprote
The regulation of vascular tone by perivascular tissues is a complex interplay of various paracrine factors. Here, we investigate the anti-contractile effect of skeletal muscle surrounding the femoral and carotid arteries and its underlying mechanisms. Using male and female Wistar rats, we demonstrated that serotonin, phenylephrine, and U-46619 induced a concentration-dependent vasoconstrictor response in femoral artery rings.
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