Publications by authors named "G F Bolasco"
Background/objectives: In Italy, the prevalence of celiac disease (CeD) among children exceeds 1.5% and has steadily increased with a linear trend over the past 25 years. The clinical presentation is heterogenous and a change in onset symptoms has been described in recent years.
View Article and Find Full Text PDFBackground: Intractable diarrhea (ID) could be defined as a syndrome of severe chronic diarrhea associated with malnutrition not easily resolved by conventional management.
Aims: To provide an overview on etiology and management of ID patients in Italy in the last 12 years.
Methods: The members of Italian Society for Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) enrolled all ID patients seen between January 1, 2011 and December 31, 2022.
Article Synopsis
- - Complement signaling helps microglia, which are brain cells, clean up and remove unnecessary connections in the brain, a process known as synaptic pruning.
- - Scientists studied mice without a special receptor called Complement receptor 3 to see how it affected the pruning process in their brains.
- - They found that these mice didn't have problems with synaptic pruning but struggled to eliminate some neurons during a crucial time, leading to thicker brain areas and stronger brain connections later on.
Refeeding Syndrome in Pediatric Age, An Unknown Disease: A Narrative Review.
J Pediatr Gastroenterol Nutr
December 2023
Refeeding syndrome (RS) is characterized by electrolyte imbalances that can occur in malnourished and abruptly refed patients. Typical features of RS are hypophosphatemia, hypokalemia, hypomagnesemia, and thiamine deficiency. It is a potentially life-threatening condition that can affect both adults and children, although there is scarce evidence in the pediatric literature.
View Article and Find Full Text PDFObjective: Recent decades have brought an increased survival of children with Neurologic Impairment (NI) but malnutrition and digestive comorbidity remain important challenges to face. We designed the present study to assess the course of nutritional status following standardized Home Enteral Nutrition (HEN) program and to evaluate impact of changing mode of feeding, as a part of overall multidisciplinary management, on digestive co-morbidity as Gastro-Esophageal Reflux Disease (GERD), Oropharyngeal Dysphagia (OPD), constipation and airway aspiration.
Methods: We performed a retrospective analysis on NI children entered into Institutional HEN program due to NI disorders between January 2011 and 2019.