[Effect of biogenic stimulators--aloe extract and biotrite--on lipid peroxidation processes in saliva in inflammatory periodontal disease].

The influence of biostimulators of vegetative origin, such as aloes and biotritis, on the process of lipid peroxidation in parodontium tissues, was studied. Biotritis has a more considerable parodontoprotective effect than aloes.

[Activity of glutamate dehydrogenase, gamma-glutamyltranspeptidase and creatine kinase in saliva in gingivitis].

In the human saliva (oral fluid), the activity of glutamate dehydrogenase tends to decrease in gingivitis and diminishes in periodontitis. That of gamma-glutamyl transpeptidase and creatine kinase increases in gingivitis. In periodontitis, their activity is higher than that in gingivitis.

[Iron in oral cavity fluid in gingival inflammation].

In parodontosis, iron levels are higher in the human gingival fluid and mixed saliva. The free iron-binding capacity of saliva is also increased. In gingivitis, higher levels of iron and free binding capacity are less evident.

[Experimental basis for the use of vitamins in the multimodal treatment of stomatological diseases].

The "Aerovit" vitamin complex prevents metabolic acidosis development and increased the rate of oxidation in tissues, which is accompanied by predominance of oxidized metabolites of glycolysis and Krebs cycles, by activation of their key enzymes as well as by an increase in the ratio of SH/SS-groups in water-soluble protein and low molecular weight fractions, by a decrease in activity of lipase. At the same time, patterns of acid-alkaline equilibrium were normalized in blood. Preventive effect of the vitamin complex was noted in treatment of the diseases accompanied by acidosis; in parodontitis the vitamins suppressed the atrophy of maxillary alveolar bone structures, normalized the acid-alkaline equilibrium in blood and decreased the rate of metabolic acidosis in liver and bone tissues.

[Indices characterizing the expression of hyperesthesia of the hard dental tissues in patients with periodontitis].

Clinical examinations of 226 patients with periodontitis have revealed in 61% of them hyperesthesia of the hard dental tissues, that was mostly generalized, characterized by a marked reaction to thermal, chemical, and tactile stimulants. Study of the mineral metabolism has demonstrated that growing bone tissue loss in dental biopsy specimens and gingival fluid is associated with reducing levels of P, Ca, and Mg. Combination of clinical manifestations of periodontitis and hyperesthesia necessitate search for combined therapy aimed at simultaneous elimination of hyperesthesia and inflammation.