Publications by authors named "G Ezpeleta"
Effectiveness of influenza vaccination in preventing confirmed influenza cases and hospitalizations in Northern Spain, 2023/24 season: A population-based test-negative case-control study.
Int J Infect Dis
December 2024
Objective: We estimated the influenza vaccination effectiveness (IVE) in preventing medical consultations and hospitalizations due to influenza during the 2023/24 season.
Methods: Two test-negative case-control studies analyzed patients who consulted primary healthcare or were hospitalized for respiratory symptoms and were tested for influenza by PCR in the 2023/24 season in Navarre, Spain. Influenza vaccination status in the current and previous seasons was compared between confirmed influenza cases and test-negative controls.
Effectiveness of Nirsevimab Immunoprophylaxis Administered at Birth to Prevent Infant Hospitalisation for Respiratory Syncytial Virus Infection: A Population-Based Cohort Study.
Vaccines (Basel)
April 2024
Article Synopsis
- Respiratory syncytial virus (RSV) is a common cause of hospitalization in newborns, but the risk decreases with age, prompting the use of nirsevimab for prevention in infants during their first RSV season.
- A study conducted in Navarre, Spain, showed that nirsevimab significantly reduced RSV hospitalizations, with a 88.7% effectiveness rate in infants who received the immunization at birth compared to those who did not.
- Immunizing infants born between October and December 2023 was found to prevent one hospitalization for every 15.3 infants immunized, suggesting that a strategy for immunization during RSV seasons could greatly reduce pediatric hospital admissions.
In Navarre, Spain, in May 2022, the seroprevalence of anti-nucleocapsid (N) and anti-spike (S) antibodies of SARS-CoV-2 was 58.9% and 92.7%, respectively.
View Article and Find Full Text PDFBackground: Ibrexafungerp (SCY-078) is the newest oral and intravenous antifungal drug with broad activity, currently undergoing clinical trials for invasive candidiasis.
Objective: The aim of this study was to assess the activity of ibrexafungerp and comparators against a collection of 434 European blood isolates of .
Methods: Ibrexafungerp, caspofungin, fluconazole, and micafungin minimum inhibitory concentrations (MICs) were collected from 12 European laboratories for 434 blood isolates, including 163 , 108 , 60 , 40 , 29 , 20 , 6 , 2 , 2 , and 1 isolate each of , , and .
Background: Analysis of polymorphic microsatellite markers (STR) is a helpful genotyping technique to differentiate Candida parapsilosis sensu stricto isolates. The aim of this study is to develop and perform an initial validation of an alternative protocol for the reliable and accurate microsatellite genotyping of C. parapsilosis sensu stricto isolates using high-throughput multiplex PCR.
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