A hand-held beta imaging probe for FDG.

Objectives: Advances in radiopharmaceuticals and clinical understanding have escalated the use of intraoperative gamma probes in surgery. However, most probes on the market are non-imaging gamma probes that suffer from the lack of ancillary information of the surveyed tissue area. We have developed a novel, hand-held digital Imaging Beta Probe™ (IBP™) to be used in surgery in conjunction with beta-emitting radiopharmaceuticals such as (18)FDG, (131)I and (32)P for real-time imaging of a surveyed area with higher spatial resolution and sensitivity and greater convenience than existing instruments.

Full-cycle steam sterilization in ophthalmic surgery-the effect of wrapping instruments.

Purpose: To determine if wrapping instruments in conjunction with full-cycle steam sterilization affects the incidence of postoperative infection in patients undergoing ophthalmic surgery in a dedicated eye center.

Design: Retrospective, consecutive-case, comparative study.

Methods: Two consecutive groups, each of approximately 19 000 ophthalmic surgical patients, were reviewed for postoperative infection.

Enhanced red and near infrared detection in flow cytometry using avalanche photodiodes.

Polychromatic flow cytometry enables detailed identification of cell phenotype using multiple fluorescent parameters. The photomultiplier tubes (PMTs) used to detect fluorescence in current instruments limit the sensitivity in the long wavelength spectral range. We demonstrate the flow cytometric applications of silicon avalanche photodiodes (APDs), which have improved red sensitivity and a working fluorescence detection range beyond 1,000 nm.

Depth of interaction resolution measurements for a high resolution PET detector using position sensitive avalanche photodiodes.

We explore dual-ended read out of LSO arrays with two position sensitive avalanche photodiodes (PSAPDs) as a high resolution, high efficiency depth-encoding detector for PET applications. Flood histograms, energy resolution and depth of interaction (DOI) resolution were measured for unpolished LSO arrays with individual crystal sizes of 1.0, 1.