[Adhesive molecules as immunologic markers of activity of multiple sclerosis].

The correlations between concentrations of the adhesive circulating molecules cICAM-1 and cVCAM-1 in the peripheral blood of patients with relapses-remitting multiple sclerosis (RRMS) in different clinical phases and magnetic resonance imaging (MRI) activity are presented. The patients in clinically active phase with Gd-enhancing lesions had elevated blood levels of cICAM-1. However, 5 patients without Gd-enhancing lesions exhibited elevated cICAM-1 and cVCAM-1 levels in active phase comparing to those in remission stage that indicate a high level of sensibility of these immunologic parameters.

[The effect of kavinton, trental, sermion and kurantil on the blood flow rate in individual segments of the cerebral arteries].

The paper shows that intravenous administration of trental, curantil, cavinton and sermion to cerebrovascular deficient patients causes a decline in blood circulation rates in the extracranial part of the carotid arteries. Sermion exhibited a biphase reaction: an increase in the blood flow followed by a decrease 15-30 minutes after introduction in the carotid arteries. Trental and curantial act in the intracranial arteries as moderate vasodilators reducing blood flow speed and blood vessel resistance.

[Diagnostic criteria of ultrasonographic methods of the study of cerebral venous circulatory failure in initial manifestations of cerebrovascular disorders].

Altogether 94 patients with initial manifestations of brain blood supply failure (IMBBSF) consequent on vegetative vascular dystonia and atherosclerosis of the cerebral vessels were examined. Clinical, echopulsographic and dopplerographic examinations demonstrated that 54 patients had cerebral venous discirculation. The main diagnostic criteria for cerebral venous discirculation in patients with IMBBSF lie in an increase of the configuration of the diastolic part of the echoPG of the cerebral arteries, possibility of recording echoPG of the cerebral veins, a rise of the linear velocity of the blood flow in the jugular veins under head-down test during dopplerography.

[Piracetam and the indicators of cerebral hemodynamics, lipid metabolism and rheological properties of blood in the initial forms of cerebrovascular disorders].

Piracetam was applied to the treatment of 60 patients with the initial manifestations of brain blood supply failure and stage I encephalopathy associated with circulatory disorders. Echopulsography of the intracranial vessels and dopplerography of the extracranial vessels of the brain were employed, changes in lipid metabolism, rheological and coagulation properties of the blood were defined. Continuous use of piracetam per os was found to produce a number of beneficial therapeutic effects.

[Diagnostic potential of phonoangiography of extracranial arteries].

Phonoangiography (PAG) was applied to study the extracranial parts of cerebral blood vessels in 16 symptom-free healthy individuals and 92 patients with cerebrovascular disorders. The conductance of cardiac tones to the cerebral arteries was assessed in comparison between PAG and phonocardiography. Correlations were found between the arterial wall elasticity, luminal changes and heart sounds conduction.