Flavor alterations in cancer treatment: Extrinsic factors as a means of augmentation.

Flavor, comprising taste, smell and somatosensory inputs, is commonly altered in patients undergoing chemotherapy resulting in malnutrition leading to cachexia. A narrative review considered taste and smell alterations associated with malignancies treated using chemotherapy and the various interventions proffered to lessen alterations. Many of the currently used interventions directed towards enhancing intrinsic factors of food appeared ineffective in encouraging intake of adequate nutrition to ward off complications of malnutrition.

Oral Health Impacts on Flavor and Significance in Dental Treatment.

The mouth is pivotal in the generation of flavor, the pleasure of eating, and the selection of food. Flavor-representing the integration of olfaction (smell) with gustation (physiologic taste) and as influenced by oral somatosenses-is rarely afforded attention in oral research and dental practice. This article considers the interrelationship between oral health and flavor and highlights gaps in current knowledge.

Growth and bone remodelling in a scorbutic rat model.

This study used the scorbutic Osteogenic Disorder Shionogi rat model and a specific diet to reliably induce a state of sub-scurvy scorbutus. Under these conditions overall somatic growth was assessed, as well as that of the caudal vertebrae, as an example of scorbutic bone growth. Tail loops were then used to mechanically stress mature caudal vertebrae under scorbutic conditions, and the vertebrae's adaptation to these applied forces was assessed, using measurements of bend deformation and histologic analysis of osteogenesis.

Cytotoxicity of gallium and indium ions compared with mercuric ion.

The use of mercury in dental amalgam restorations has become the subject of political controversy despite its long history of safe clinical use, and alternative materials based on gallium and indium rather than mercury have been developed. The biological safety of these metals must be evaluated, as part of their assessment as mercury substitutes. The cytotoxicities of mercury (II) nitrate, gallium (III) nitrate, and indium (III) nitrate were assessed at concentrations between 0.

Sealing ability of three materials used to repair lateral root perforations.

Thirty-five extracted single-rooted human teeth were decoronalized, root filled with AH-26 and gutta-percha, and perforated at the apical one third level. Repairs of the lateral perforations were carried out with three materials: amalgam plus cavity varnish, EBA cement, and silver glass-ionomer cement. Negative controls were not perforated and positive controls had unrepaired perforations.