PK and PK/PD of doxycycline in drinking water after therapeutic use in pigs.

A commercial doxycycline formulation was administered in drinking water to 12 pigs at the recommended dose of 10 mg/kg daily for 5 days. The mean plasma concentration at steady-state was 1.37 +/- 1.

Tylosin depletion from edible pig tissues.

The depletion of tylosin from edible pig tissues was studied following 5 days of intramuscular (i.m.) administration of 10 mg/kg of tylosin to 16 crossbreed pigs.

Disposition kinetics of tylosin administered intravenously and intramuscularly to pigs.

The distribution of tylosin was studied using a crossover design, in six pigs following i.v. and i.

Disposition of oxytetracycline in pigs after i.m. administration of two long-acting formulations.

Two commercially available long-acting oxytetracycline (OTC) formulations were administered by the intramuscular (i.m.) route to six healthy pigs at the recommended dose of 30 mg/kg.

Thiamphenicol disposition in pigs.

Pharmacokinetic parameters of thiamphenicol (TAP) were determined after intravenous (i.v.) and intramuscular (i.