Iohexol clearance for renal function measurement in gynaecologic cancer patients.

Purpose: To determine a valid and practical routine for glomerular filtration rate measurement in gynaecologic cancer patients.

Material And Methods: The established method, endogenous creatinine clearance, was compared to 51Cr-EDTA clearance and contrast medium clearance in 68 women with various gynaecologic carcinomas. Contrast medium clearance was determined in association with conventional urography (iohexal 300 mg I/ml, 40 ml) for evaluation of urinary tract involvement by the tumour.

Radioimmunoscintigraphy of gynecologic tumors with 131I-labeled anti-PLAP monoclonal antibodies.

Radioimmunoscintigraphy (RIS) was performed in 20 patients with gynecologic tumors, 14 ovarian, 5 cervical, and one endometrial carcinoma. One murine monoclonal antibody (mab) against placental alkaline phosphatase (H7) was used after radiolabeling with 131I. The labeling procedure yielded antibodies with specific activity varying between 60 and 73 MBq/mg mab.

Conservative surgery for vulvovaginal melanoma.

22 cases of vulvovaginal melanoma seen in Umeă between 1963 and 1989 were retrospectively reviewed. According to FIGO, 11 were in Stage I, 6 in Stage II, 3 in Stage IV and 2 in Stage VI. Most patients received only conservative surgery and/or radiotherapy.