Publications by authors named "G Ebrahimipour"
Bariatric surgery is vital for sustainable weight loss and metabolic improvement in obese individuals, but its effects on gut microbiota and their role in these benefits require further investigation. Investigate the temporal changes in gut microbiota in obese patients undergoing bariatric surgery (gastric sleeve gastrectomy or Roux-en-Y Gastric Bypass (RYGB)) compared to healthy controls, aiming to understand their role in weight loss and metabolic health improvement. A case-control study included 30 obese patients aged 65-95 undergoing bariatric surgery, and 18 matched healthy controls.
View Article and Find Full Text PDFsignificantly contributes to nosocomial infections and necessitates research into novel treatment methods. For the first time, this research evaluated the immunoprotective potential of recombinant PAPI-1 encoded type IV pili targeting in BALB/C mice. The target sequence was identified, and a PilS2-encoding vector was constructed.
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- Several vaccine candidates have been developed for Pseudomonas aeruginosa, but none are currently effective in the market, largely due to the pathogen's multiple drug-resistant forms and virulence factors.
- The study introduces a chimeric PilS2 immunogen that successfully stimulates immune responses in mice, addressing the challenge of targeting the diverse T4P subtypes.
- These findings suggest that PilS2 pilin shows promise as a new immunogen and could pave the way for effective immunotherapy strategies against this harmful pathogen.
Background: Although the etiopathogenesis of inflammatory bowel disease (IBD) is still poorly understood, has been described as a potential causative microorganism in IBD pathogenesis and also disease progression, offering a potential therapeutic target for disease management. Therefore, we conducted this study to investigate the pathotypes, phylogenetic groups, and antimicrobial resistance of isolates from patients with IBD in Iran.
Methods: Fecal and biopsy colonic samples were collected from IBD patients experiencing flare-up episodes referred to Taleghani hospital in Tehran, Iran, between August 2020 and January 2021.
A novel myxobacterial strain ZKHCc1 1396 was isolated in 2017 from a soil sample collected along Chalus Road connecting Tehran and Mazandaran, Iran. It was a Gram-negative, rod-shaped bacterial strain that displayed the general features of including gliding and fruiting body formation on agar and microbial lytic activity. Strain ZKHCc1 1396 was characterized as an aerobic, mesophilic, and chemoheterotrophic bacterium resistant to many antibiotics.
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