Publications by authors named "G E York"
Importance: Blast-related mild traumatic brain injuries (TBIs), the "signature injury" of post-9/11 conflicts, are associated with clinically relevant, long-term cognitive, psychological, and behavioral dysfunction and disability; however, the underlying neural mechanisms remain unclear.
Objective: To investigate associations between a history of remote blast-related mild TBI and regional brain volume in a sample of US veterans and active duty service members.
Design, Setting, And Participants: Prospective cohort study of US veterans and active duty service members from the Long-Term Impact of Military-Relevant Brain Injury Consortium-Chronic Effects of Neurotrauma Consortium (LIMBIC-CENC), which enrolled more than 1500 participants at 5 sites used in this analysis between 2014 and 2023.
Unlabelled: The study of animal movement provides insights into underlying ecological processes and informs analyses of behaviour and resource use, which have implications for species management and conservation. The tools used to study animal movement have evolved over the past decades, allowing for data collection from a variety of species, including those living in remote environments. Satellite-linked radio and GPS collars have been used to study polar bear () ecology and movements throughout the circumpolar Arctic for over 50 years.
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- This study explores the connection between white matter hyperintensities (WMHs), mild traumatic brain injury (mTBI), age, and cognitive performance in a group of combat-exposed Veterans and Service Members.
- The research involved 1,011 participants, revealing that both groups had similar rates of WMHs; however, older individuals with mTBI showed a higher count of WMHs compared to those without.
- Significant relationships were found linking increased WMHs with cognitive impairments in memory and processing speed, suggesting the need for further investigation on the long-term effects of WMHs in mTBI cases.
Article Synopsis
- MRI is a key tool in researching diagnostic and prognostic markers after traumatic brain injury (TBI), particularly to understand mild TBI (mTBI), but findings are often inconsistent, highlighting the need for further study.
- The study analyzed MRI data from 976 military veterans and service members to explore the links between imaging outcomes and clinical features of mTBI, using regression models to account for factors like age and sex.
- Results indicated that while no major differences were found between those with and without mTBI history, blast-related mTBI showed significant brain volume reductions in certain areas, and multiple mTBIs correlated with specific MRI findings.
Mild traumatic brain injury (mTBI) is the most common form of brain injury. While most individuals recover from mTBI, roughly 20% experience persistent symptoms, potentially including reduced fine motor control. We investigate relationships between regional white matter organization and subcortical volumes associated with performance on the Grooved Pegboard (GPB) test in a large cohort of military Service Members and Veterans (SM&Vs) with and without a history of mTBI(s).
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