Plant Metabolic Network 16: expansion of underrepresented plant groups and experimentally supported enzyme data.

The Plant Metabolic Network (PMN) is a free online database of plant metabolism available at https://plantcyc.org. The latest release, PMN 16, provides metabolic databases representing >1200 metabolic pathways, 1.

Cumulative Trauma Exposure and Post-Traumatic Stress Symptoms among Older Adults in South Africa: Does Post-Traumatic Growth Moderate this Link?

The study explored the interplay between PTG and PTSS in older South African adults exposed to trauma. A quantitative cross-sectional design was employed. 195 participants from a low-resourced setting in South Africa were interviewed using the UCLA Life Adversities Screener, the PTSD Checklist (DSM-5), and the PTG-Inventory.

Loss of STING impairs lactogenic differentiation.

Heightened energetic and nutrient demand during lactogenic differentiation of the mammary gland elicits upregulation of various stress responses to support cellular homeostasis. Here, we identify the stimulator of interferon genes (STING) as an immune supporter of the functional development of mouse mammary epithelial cells (MECs). An in vitro model of MEC differentiation revealed that STING is activated in a cGAS-independent manner to produce both type I interferons and proinflammatory cytokines in response to the accumulation of mitochondrial reactive oxygen species.

Evaluation of a nature-based virtual reality intervention to support hospice caregivers: a pilot feasibility study.

Objectives: Hospice family caregivers (CGs) may experience poor emotional health and diminished quality of life (QOL) secondary to stressors that accompany home-based end-of-life caregiving. Innovative flexible strategies are needed to support hospice CGs in their homes. Being outdoors in nature enhances well-being but is often not accessible to home-based CGs.