Daily magnesium supplementation effect on magnesium deficiency in rats during prolonged restriction of motor activity.

The objective of this investigation was to evaluate the effect of magnesium (Mg) supplements in rats during prolonged restriction of motor activity (hypokinesia [HK]) and in the presence of Mg deficiency, which is characterized by increased rather than decreased plasma Mg concentration, as occurs in ambulatory conditions. The studies were performed during 98 days of HK on 100 13-week-old Sprague-Dawlay male rats weighing 360 to 390 g. They were equally divided into four groups: (1) unsupplemented control animals (UCA), (2) unsupplemented hypokinetic animals (UHA), (3) supplemented control animals (SCA), and (4) supplemented hypokinetic animals (SHA).

Electrolyte metabolic changes in rats during and after exposure to hypokinesia.

The objective of this study was to determine fluid-electrolyte changes in male Wistar rats during 90 days of hypokinesia (decreased motor activity) and 15 days posthypokinesia. The animals were divided into two groups: rats subjected to hypokinesia served as experimental animals and rats placed under vivarium conditions served as control animals. The hypokinetic effect was carried out by keeping the experimental rats in small individual cages which restricted all their movements without hindering food and water intake.

Fluid-electrolyte changes in physically conditioned subjects after hypokinesia and chronic hyperhydration.

The aim of this study was to determine whether fluid-electrolyte changes, which are developed during prolonged hypokinesia (decreased number of km per day), can be prevented or minimized with the use of a daily intake of fluid and salt supplementation (FSS). The experiments on hypokinesia (HK) were performed for 364 days on 18 endurance-trained male volunteers in the age range of 21-23 years, with an average maximum oxygen uptake of 67 ml kg-1. All volunteers were divided into three equal groups: six volunteers were placed on a continuous regime of exercise of 14.

Renal excretion of end products of protein metabolism in urine of endurance trained subjects during restriction of muscular activity.

The objective of this investigation was to determine the rate of renal excretion of end products of protein metabolism in urine of 20 endurance trained male volunteers aged 23-26 years with an average maximum oxygen uptake of 66 ml.kg-1.min-1 during 364 days of hypokinesia (decreased number of running steps/day).

Mineralization of human bone tissue under hypokinesia and physical exercise with calcium supplements.

It has been suggested that physical exercise and calcium supplements may be used to prevent demineralization of bone tissue under hypokinesia (diminished muscular activity). Thus, the aim of this study was to determine mineral content of bones of 12 physically healthy men aged 19-24 years under 90 days of hypokinesia and intensive physical exercise (PE) with calcium lactate (C) supplements. They were divided into experimental and control groups with 6 men in each.