[Diagnosis and new treatment options for pituitary adenomas].

Currently, the treatment of pituitary adenomas is inextricably linked with transsphenoidal neurosurgical intervention. Modern technologies used in surgery for this pituitary pathology, such as endoscopy using angled optics, as well as the use of specialized instruments, sealing and hemostatic materials, increase the effectiveness of surgical treatment of pituitary adenomas and reduce the incidence of intraand postoperative complications. The development of radiation methods of diagnostics, such as MRI, makes it possible to more accurately identify the formation of the pituitary gland, assess its size, direction of growth, and the degree of invasion of surrounding tissues.

[Redo laparoscopic surgery for recurrent gastroesophageal reflux disease and hiatal hernia].

Aim: To assess mechanisms of recurrent gastroesophageal reflux disease and the ability to perform adequate surgical correction after previous surgery.

Material And Methods: The authors from various surgical centers have operated 2678 patients with gastroesophageal reflux disease and hiatal hernia for the period 1993-2018. 127 (4.

[On the question of heart injuries].

The work is devoted to an analysis of hospitalized patients to the specialized department of injuries of the chest and abdomen of the Mariinskaja hospital at the period from 1993 through 2010. The diagnosis of injury of the pericardium and heart had 280 patients, during the operative treatment heart injuries were detected in 156 (55.71%) patients.

[Application of chromatography methods for the diagnostics of systemic inflammation].

Specific manifestations of systemic inflammation in patients with acute destructive cholecystitis in the postoperative period were studied by the methods of high-precision exclusive liquid chromatography with chromatograph "Trirotar" (Japan) with columns "Polysep G-5", "Toyopearl-Sw - 2000-2500". It was found that systemic inflammation was accompanied by active accumulation of middle- and low-molecular mass. Later their spectrum was found to change when going over to unfavorable clinical course.