Publications by authors named "G E Serra"
I need to thank my colleagues for their valuable comments on the recently published paper entitled "Identification of Achille's Tendon Tears: Diagnostic Accuracy of Dual-Energy CT with Respect to MRI" [...
View Article and Find Full Text PDFThe elevated plus maze (EPM) apparatus consists of two open arms that provide aversive spaces and two closed arms that provide protective and welcoming spaces. Here, we present a protocol to implement the classical EPM apparatus in a real-time optogenetic environment to address behavioral avoidance in mice. We describe steps for performing stereotaxic surgery, mouse manipulation, and experimental setup.
View Article and Find Full Text PDFBackground And Objective: Currently, the management for pituitary apoplexy (PA) has been promoted toward a more conservative approach, particularly for patients with low-grade PA scores. Our aim was to investigate trends in PA management and compare clinical presentation, therapeutic approaches, and outcomes before and after 2017, additionally to evaluate long-term outcomes in conservatively treated patients.
Methods: Spanish multicenter, retrospective study.
Article Synopsis
- The study focuses on identifying genetic mutations in malaria parasites that confer drug resistance, essential for improving surveillance and target discovery in malaria treatment.
- Researchers analyzed the genomes of 724 clones resistant to 118 different antimalarial compounds, uncovering 1,448 variants in 128 frequently mutated genes related to multidrug resistance.
- The findings suggest that in vitro selected mutations are more diverse and significant than naturally occurring ones, providing insights into how these mutations can inform predictions of drug resistance in similar pathogens.
Background Because of its ability to help assess the presence of subtle morphologic changes in bone and bone marrow edema, dual-energy CT (DECT) could be an alternative to MRI in the diagnosis of bone stress injury that includes a stress fracture (SF) and stress reaction (SR). Purpose To determine the diagnostic accuracy of DECT in identifying bone stress injury of the lower limb using MRI as the reference standard. Materials and Methods This prospective study, conducted between June 2021 and January 2024, included consecutive patients clinically suspected of having stress injury (SF or SR) of the lower limb (leg, ankle, or foot).
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