Publications by authors named "G E Seker"
Clinical and Molecular Analysis in Patients with Peutz-Jeghers Syndrome.
Turk J Gastroenterol
March 2024
Article Synopsis
- Peutz-Jeghers syndrome (PJS) is a rare genetic disorder linked to heightened cancer risk, primarily due to mutations in the STK11 gene, with a study focusing on its manifestations and genetic profiles among 20 patients across 14 families.
- The research found that typical symptoms began around 18.9 years of age, with common issues including abdominal pain and specific polyps; 85% of patients had mucocutaneous lesions, and dysplastic polyps were present in some cases, leading to a few malignancies.
- The study successfully identified multiple pathogenic mutations, including 3 novel variants, and achieved high diagnostic rates with genetic testing; notable findings indicate that patients without mutations tend to show later symptom
Background: Gastrointestinal system disorders are known to be prevalent among children with autism spectrum disorder (ASD). Some ASD-associated comorbidities are abdominal pain, constipation, diarrhea, gastroesophageal reflux, sleep disturbances, epilepsy, and psychiatric problems. Nonetheless, there is still limited information about the presence of functional GI disorders (FGIDs) among children with ASD, especially in Türkiye.
View Article and Find Full Text PDFEvaluation of bioactivities of L. hull extracts as a potential antimicrobial and antioxidant natural source.
Food Sci Technol Int
December 2024
L. hull, a the major byproduct of pistachio processing, is a source of functional compounds with antioxidant and antimicrobial activities. The extraction of these natural compounds from pistachio hulls and their use instead of synthetic chemicals has gained great attention.
View Article and Find Full Text PDFObjectives: Large cell calcifying Sertoli cell tumours (LCCSCTs) are one of the infrequent causes of prepubertal gynaecomastia. Most of these tumours are in the content of Peutz-Jeghers syndrome (PJS) or other familial syndromes (Carney complex).
Case Presentation: Here, we report a long-term follow-up of an 8.