Publications by authors named "G E Papanikolaou"

Prune belly syndrome (PBS), or Eagle-Barrett syndrome, is a rare congenital disorder marked by abdominal wall muscle deficiency, urinary tract anomalies, and cryptorchidism, causing significant abdominal wall laxity and functional impairment. This case report discusses an innovative approach to abdominal wall reconstruction in a 19-year-old male patient with PBS and associated conditions, including chronic renal failure and spina bifida. Previously, he underwent distal ureterectomy and vesicoureteral reimplantation at the age of two years to correct urinary tract dilation and bilateral orchiopexy.

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Anorectal melanoma (ARM) is a rare entity with aggressive biological behavior and poor prognosis. Clinically, ARM presents with atypical symptoms, such as anal pain and bleeding, thus often being misdiagnosed as a benign anorectal pathology and leading to delayed diagnosis. We present a case of a 73-year-old female patient with stage I ARM, treated successfully with a combination of neoadjuvant-adjuvant immunotherapy (nivolumab, an anti-PD-1 monoclonal antibody) and abdominoperineal resection.

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Venous leg ulcers (VLUs) are hard-to-heal wounds and are prone to microbial colonization. Innovative and improved therapies are thus required to resolve local infection and enhance the wound healing process. The objective of this study was to evaluate the effectiveness of medical-grade honey (MGH) for the treatment of clinically infected and non-healing VLUs.

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Landfill leachate is a multicomponent aqueous matrix generated by the percolation of rainwater into the body of a landfill. Considering its content of natural and xenobiotic components, it must be considered as a waste, whose composition depends on type of waste, biodegradation processes, rainwater, composition and compaction of waste and their age; these factors influence the transport, absorption, toxicity, bioaccumulation of the contaminants. Leachates sampled from landfill and downhill piezometers, in periods characterized by different rainfall, were studied by ATR-FTIR and SEM-EDX techniques; analyses were carried out on dried and calcinated residues obtained at T = 383 and 923 K, respectively.

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