Publications by authors named "G E Papageorgiou"

We report the pressure-temperature (-) phase diagram, the origin of the subglass dynamics, and the crystallization kinetics of the biobased polyester poly(ethylene 2,5-furanoate) (PEF), through dielectric spectroscopy (DS) measurements performed as a function of temperature and pressure. The phase diagram comprises four different "phases"; glass, quenched melt, crystalline, and normal melt. The cold crystallization temperature, , increases linearly with pressure (according to the Clausius-Clapeyron equation) as / ∼ 240 K·GPa and is accompanied by a small change in specific volume (Δ = 0.

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Super-resolution ultrasound (SRU) is a new ultrasound imaging mode that promises to facilitate the detection of microvascular disease by providing new vascular bio-markers that are directly linked to microvascular pathophysiology, thereby augmenting current knowledge and potentially enabling new treatment. Such a capability can be developed through thorough understanding as articulated by means of mathematical models. In this study, a 2D numerical flow model is adopted for generating flow adaptation in response to ischaemia, in order to determine the ability of SRU to register the resulting flow perturbations.

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CircHomer1 is an activity-dependent circular RNA (circRNA) isoform produced from back-splicing of the Homer1 transcript. Homer1 isoforms are well-known regulators of homeostatic synaptic plasticity through post-synaptic density scaffold regulation. Homer1 polymorphisms have been associated with psychiatric diseases including schizophrenia (SCZ) and bipolar disorder (BD).

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Article Synopsis
  • The study investigates how microcirculation alterations can indicate vascular pathologies, particularly through methods like contrast enhanced ultrasound (CEUS) and super-resolution ultrasound (SRU) imaging.
  • CEUS showed limitations in accurately measuring blood flow in microvascular areas due to interference from larger vessels and varying degrees of blood flow redistribution, which affected correlation with actual flow rates.
  • In contrast, SRU demonstrated high accuracy in depicting blood vessel structures and dynamics, achieving over 91% correspondence with ground truth measurements, suggesting it may be a more effective tool for studying subtle flow changes caused by ischaemia.
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