Publications by authors named "G E Liwszyc"
Article Synopsis
- - The comet assay is a flexible method used to identify DNA damage in individual eukaryotic cells, applicable to various species from yeast to humans, detecting issues like DNA strand breaks and other forms of damage.
- - Modifications to the protocol are necessary based on the specimen to minimize additional DNA damage during sample processing and to enhance the detection of damage differences.
- - The method has been validated for various applications in research and has gained recognition as an in vivo genotoxicity test by the OECD, with guidelines provided for its use across different cell types and DNA damage assessments.
Cross-linking of B cell antigen receptor (sIg) elicits different biological responses, including cell activation, proliferation, differentiation, anergy and cell death depending on the maturational stage of the cell. We established the tumor cell lines HF-1.3.
View Article and Find Full Text PDFAntigen-triggered response in T cells is mediated by the T cell receptor (TCR)/CD3-complex. This signalling, however, is modulated by a number of other surface molecules. Among the most important of these is the CD4/CD8 molecule which associates with the TCR/CD3-complex and binds to the MHC complex.
View Article and Find Full Text PDFActivation of protein tyrosine kinases (PTK) is an initial and obligatory event for the triggering of human natural killer (NK) cells to cytotoxicity. Of the different PTK detected in NK cells, only p56lck has previously been shown to participate in NK cell activation. Here we present evidence that another PTK, p72syk, is involved in activation of NK cells.
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