Publications by authors named "G E HALL"
Background: Primary coenzyme Q10 (CoQ10) deficiency is an autosomal recessive genetic disease caused by mitochondrial dysfunction. Variants in Coenzyme Q8B () can cause primary CoQ10 deficiency. -related glomerulopathy is a recently recognized glomerular disease that most often presents as steroid-resistant nephrotic syndrome (SRNS) in childhood.
View Article and Find Full Text PDFAntarctic environments are dominated by microorganisms, which are vulnerable to viral infection. Although several studies have investigated the phylogenetic repertoire of bacteria and viruses in these poly-extreme environments with freezing temperatures, high ultra violet irradiation levels, low moisture availability and hyper-oligotrophy, the evolutionary mechanisms governing microbial immunity remain poorly understood. Using genome-resolved metagenomics, we test the hypothesis that Antarctic poly-extreme high-latitude microbiomes harbour diverse adaptive immune systems.
View Article and Find Full Text PDFPurpose: Assessing the long-term impact of cancer on people's lives is challenging due to confounding issues such as aging and comorbidities. We aimed to investigate this impact by comparing the outcomes of cancer survivors with a matched control cohort.
Methods: This was a cross-sectional survey of breast, colorectal and ovarian cancer survivors approximately 5 years post-diagnosis and a cohort of age, sex and social deprivation-matched controls who had never had a cancer diagnosis.
Article Synopsis
- The study focuses on detecting multijet signatures from proton-proton collisions at a high energy of 13 TeV, analyzing a dataset totaling 128 fb^{-1}.
- A special data scouting method is utilized to pick out events with low combined momentum in jets.
- This research is pioneering in its investigation of electroweak particle production in R-parity violating supersymmetric models, particularly examining hadronically decaying mass-degenerate higgsinos, and it broadens the limits on the existence of R-parity violating top squarks and gluinos.
Article Synopsis
- The study compares egg production in two turkey lines: the high egg-producing Ohio State University E line and a lower producing random-bred control (RBC1) line, highlighting the importance of understanding these differences for improving flock profitability.
- E line hens outperformed RBC1 hens by producing 20% more eggs, with their egg production advantage linked to longer clutch lengths rather than an increase in the number of preovulatory follicles.
- Gene expression analysis showed that E line hens had alterations in the expression of key reproductive genes, suggesting that differences in hormone synthesis may allow their follicles to develop more efficiently, ultimately enhancing egg production without increasing follicle numbers.