Publications by authors named "G E GUTMANN"

Article Synopsis
  • The study investigates how physical exercise impacts working memory (WM) and brain activity in patients with Major Depression Disorder (MDD), focusing on the hippocampus.
  • A total of 86 MDD patients participated in a 12-week program, divided into high intensity exercise (HEX), low intensity exercise (LEX), and a waiting list control group, with an n-back WM task used to measure cognitive performance before and after interventions.
  • Results showed that both exercise groups improved their WM performance, particularly the HEX group, which also exhibited increased neural activation in the left hippocampus, though there were no significant structural changes in brain volume.
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Background: Deficits in cognition like working memory (WM) are highly prevalent symptoms related to major depressive disorder (MDD). Neuroimaging studies have described frontoparietal abnormalities in patients with MDD as a basis for these deficits. Based on research in healthy adults, it is hypothesized that increased physical fitness might be a protective factor for these deficits in MDD.

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This paper describes the design philosophy for our cloud-based virtual reality (VR) co-creation environment (CCE) for molecular modeling. Using interactive VR simulation can provide enhanced perspectives in molecular modeling for intuitive live demonstration and experimentation in the CCE. Then the use of the CCE can enhance knowledge creation by bringing people together to share and create ideas or knowledge that may not emerge otherwise.

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The current pilot study investigated if interference control can be improved by a three-week at-home training comprising a flanker and a n-back task in healthy adults, thus exploring the training's suitability for future clinical application, i.e. as a treatment augmentation for psychological disorders.

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Boundary conditions are important for pattern formation in active matter. However, it is still not well-understood how alterations in the boundary conditions (dynamic boundary conditions) impact pattern formation. To elucidate the effect of dynamic boundary conditions on the pattern formation by active matter, we investigate an gliding assay of microtubules on a deformable soft substrate.

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