Publications by authors named "G E GEN"
Article Synopsis
- The study focuses on Brg1, a key protein involved in chromatin remodeling, and its impact on airway inflammation induced by house dust mites (HDM).
- Researchers used wild-type and Brg1 knockout mice, as well as bronchial epithelial cells, to analyze how Brg1 influences inflammatory responses and mucus production related to asthma.
- Results indicate that Brg1 knockout mice showed lower levels of airway inflammation and mucus secretion compared to wild-type mice, suggesting that Brg1 plays a significant role in exacerbating asthma symptoms via the JAK1/2-STAT6 signaling pathway.
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