Publications by authors named "G Duque"
Sarcopenia is an age-related muscle disorder that increases risks of adverse clinical outcomes, but its treatments are still limited. Gut microbiota is potentially associated with sarcopenia, and its role is still unclear. To investigate the role of gut microbiota in sarcopenia, we first compared gut microbiota and metabolites composition in old participants with or without sarcopenia.
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- Aging leads to physiological changes and increased disease vulnerability, culminating in higher mortality rates as individuals get older.
- Regular physical activity (PA) and exercise can counteract aging effects, improve health span, and reduce the risk of chronic diseases such as heart disease and cancer.
- Personalized exercise plans, including various forms of training like aerobic and resistance exercises, are essential for maintaining health and functionality in older adults, particularly those with age-related issues.
Frailty complicates the care of individuals with dementia, increasing their vulnerability to adverse outcomes. This Personal View presents expert recommendations for managing frailty in individuals with dementia, aimed at health-care providers, particularly those in primary care. We conducted a rapid literature review followed by a consensus process involving 18 international experts on dementia and frailty.
View Article and Find Full Text PDFObjectives: Findings regarding the effects of vitamin D supplementation on diabetes risk are inconclusive. Because inflammation and vitamin D levels are interconnected, we hypothesized that higher inflammation levels moderate the effects of vitamin D deficiency on diabetes risk.
Design, Setting, Participants, And Measurements: UK Biobank participants without pre-existing diabetes at baseline were included (N = 336,500).
Background: Prostate cancer is the second most common neoplasm in men, with projections estimating over one million new cases by 2045. Differentially expressed genes can significantly enhance the diagnosis, treatment, monitoring, and prognosis of this disease.
Purpose: to systematically review and analyze validated differentially expressed mRNAs in prostate cancer patients to propose a robust molecular profile for clinical diagnostics.