Publications by authors named "G Donzelli"

Italy was among the first countries in Europe to be heavily impacted by the outbreak of COVID-19. Northern Italy and Lombardy, in particular, were the most affected areas. In September 2021, the team of "AIS, the digital turn" (AISdt), a project whose objectives include collecting data in 50 locations in Italy, across Lombardy and Piedmont, resumed in-person data collection.

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Article Synopsis
  • Toxicology and epidemiology are crucial public health fields that help investigate the health impacts of toxic substance exposure, with various frameworks for evidence integration evolving since 2011.
  • Collaboration among scientists from different disciplines, such as toxicologists, epidemiologists, and risk assessors, is essential for effective risk assessment aligned with regulatory goals.
  • Implementing transparent literature searches, systematic protocols for evidence collection, tailored quality assessment tools, and the Adverse Outcome Pathway framework can enhance the understanding and integration of toxicological data.
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Article Synopsis
  • This study examines how the TAS2R38 gene, linked to bitter taste perception, affects nasal nitric oxide (nNO) levels and respiratory infections in patients with primary ciliary dyskinesia (PCD).
  • Researchers tracked 119 PCD patients over 10 years, comparing different TAS2R38 haplotypes and their correlation with nNO and lung function outcomes.
  • Findings indicate that the PAV/PAV haplotype leads to higher nNO levels and better lung function in those with certain PCD mutations, suggesting TAS2R38 may influence the severity of mild PCD and guide future treatment strategies.
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