Publications by authors named "G Dodd"
This perspective article is a product of the work of an expert group within the Prebiotic Task Force convened by the International Life Sciences Institute Europe, a non-profit organization that brings together experts from academia, industry, and public service to catalyze nutrition science for public benefit. An expert group was conceived in October 2023 to discuss the evidence base on the use of prebiotics to promote cognitive functioning, with a focus on highlighting knowledge gaps and proposing a list of recommendations to guide this specific area of research forward. To address this, we evaluated existing systematic reviews and meta-analyses of human intervention studies that examine the effects of prebiotics on cognitive functioning.
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- Metabolic diseases like obesity and type 2 diabetes involve insulin resistance, particularly in neurons of the arcuate nucleus of the hypothalamus that help regulate metabolism.
- The study highlights how the perineuronal net, an extracellular matrix that surrounds these neurons, becomes altered during metabolic diseases, contributing to insulin resistance.
- Disrupting this protective net in obese mice improves brain insulin access, reverses insulin resistance in neurons, and boosts metabolic health, revealing extracellular matrix changes as critical to understanding metabolic diseases.
Personalised dietary advice has become increasingly popular, currently however most approaches are based on an individual's genetic and phenotypic profile whilst largely ignoring other determinants such as socio economic and cognitive variables. This paper provides novel insights by testing the effectiveness of personalised healthy eating advice concurrently tailored to an individual's socio-demographic group, cognitive characteristics, and sensory preferences. We first used existing data to build a synthetic dataset based on information from 3654 households (Study 1a), and then developed a cluster model to identify individuals characterised by similar socio-demographic, cognitive, and sensory aspects (Study 1b).
View Article and Find Full Text PDFThe sound transmission loss (STL) of wall partitions, especially in the coincidence region, is investigated. A Mindlin plate with periodically attached masses in a periodic "supercell" pattern is analyzed theoretically and experimentally for sound attenuation. Modeling the masses as points, analytical expressions for predicting the dispersion relation and frequency bandgaps of the plate are developed.
View Article and Find Full Text PDFGlucagon-like peptide receptor (GLP-1R) agonists (e.g., semaglutide, liraglutide, etc.
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