Publications by authors named "G Di Giorgio"

Introduction: Peyronie's disease (PD) is characterized by fibrosis of the penile tunica albuginea. Conservative treatment options may involve oral and/or injectable medications.

Materials And Methods: This case series includes four patients with PD in the first phase.

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Introduction: Immune checkpoint inhibitor (ICI)-based immunotherapy targeting programmed cell death 1 (PD-1) or its ligand 1 (PD-L1) has radically changed the management of many types of solid tumors including non-small cell lung cancer (NSCLC). Many clinical trials have demonstrated that ICIs improve the survival and the quality of life of patients with advanced non oncogene NSCLC as compared to standard therapies. However, not all patients achieve a clinical benefit from this immunotherapeutic approach.

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Article Synopsis
  • B-mode ultrasound (US) is effective in diagnosing Peyronie's disease (PD), but real-time elastography (RTE) enhances the detection of elusive penile plaques that standard US may miss.
  • The study involved 37 PD patients and demonstrated that combining RTE with standard US detected all non-palpable plaques (100% detection) compared to 61.5% with just standard US.
  • RTE also proved useful for monitoring treatment progress in PD patients, showing a significant correlation between plaque volume and diagnostic indicators throughout the treatment process.
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The design and development of engineered micro and nano-carriers offering superior therapeutic performance compared to traditional delivery forms, are crucial in pharmaceutical research. Aerosolization and inhalation of carriers with improved solubility/stability of insoluble drugs, has huge potential for targeted drug delivery (DD) in various pulmonary diseases. Indeed, dedicated carriers must meet specific dimensional rules for proper lung delivery.

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For children living in the urban slums of Nairobi (Kenya), primary health conditions are not guaranteed, and oral diseases add further concern at social and institutional levels beyond the general poverty conditions. This study aims at determining the factors that influence the oral health status of children living in Nairobi slums. A cross-sectional study on school-aged subjects was conducted in June 2022 in three urban slum areas of Nairobi through a pediatric dental screening.

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