Effects of Acyl Chain Unsaturation on Activation Energy of Water Permeability across Droplet Bilayers of Homologous Monoglycerides: Role of Cholesterol.

Cholesterol is an important component of total lipid in mammalian cellular membranes; hence, the knowledge of its association with lipid bilayer membranes will be essential to understanding membrane structure and function. A droplet interface bilayer (DIB) provides a convenient and reliable platform through which values for permeability coefficient and activation energy of water transport across the membrane can be extracted. In this study, we investigated the effect of acyl chain structure in amphiphilic monoglycerides on the permeability of water across DIB membranes composed of cholesterol and these monoglycerides, where the acyl chain length, number of double bonds, and the position of double bond are varied systematically along the acyl chains.

Gradual bone distraction in craniosynostosis. Preliminary results in seven cases.

Seven patients with craniosynostosis (mean age 8 years, Apert syndrome, n = 4, Crouzon's disease, n = 3) underwent lengthening of the skull by gradual bone distraction. Three patients (group A) were treated by coronal craniectomy reaching the orbital fissure and gradual bone distraction. The other four (group B) underwent monobloc craniofacial disjunction and gradual bone distraction.