Effects of therapeutic alliance on patients with major depressive disorder: a literature review.

Therapeutic alliance refers to the collaborative relationship between a therapist and a patient, a concept widely explored in clinical research. It has emerged as a crucial component of effective psychotherapeutic interventions, particularly in the treatment of major depressive disorder (MDD), where its role appears to be multifaceted. In this context, we reviewed the main literature on the role of therapeutic alliance in MDD.

White matter changes in paediatric bipolar disorder: A systematic review of diffusion magnetic resonance imaging studiesA systematic review of diffusion magnetic resonance imaging studies.

Background: Paediatric bipolar disorder (PBD) is characterized by severe mood fluctuations that deviate from typical childhood emotional development. Despite the efforts, the pathophysiology of this disorder is not well understood yet. In this review, we aimed to synthesize existing diffusion magnetic resonance imaging (dMRI) research findings in PBD.

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The increase of Youth Mental health both internationally and locally has led the Department of Mental Health and Addictions of the Melegnano and Martesana Territorial Health Hospital, located in the southeast of the Milan area, to initiate an organizational and training process to revisit the care access for young people aged 14 to 24. The objective is to innovate the care pathway by optimizing diagnostic, care, and rehabilitative processes, while enhancing cross-departmental skills. The training program, which lasted one year and was led by a tutor, focused on analyzing organizational aspects, user needs, and existing constraints.

Assessing the efficacy of metacognitive therapy as monotherapy or adjunctive treatment in patient suffering from major depression and dysthimia: A comprehensive review of clinical trials.

Background: Depression is one of the most widespread diseases worldwide, with the highest rates of disability. Considering its chronic course, over the years several treatment options have been developed and validated, however still with high relapse rates. Therefore, in recent years, the so-called third wave psychotherapies have been developed for the treatment of psychiatric disorders.