Publications by authors named "G Del Fabro"
Objectives: Mid-regional pro-adrenomedullin (MR-proADM) and monocyte CD169 (CD169) are valuable prognostic indicators of severe COVID-19.
Methods: We assessed the predictive ability of a single measurement of MR-proADM and CD169 at emergency department (ED) admission to forecast in-hospital and 60-day mortality in adult COVID-19 patients. We analyzed clinical and laboratory data, with in-hospital mortality as the primary endpoint and 60-day mortality as the secondary endpoint.
Hyaloperonospora arabidopsidis (Hpa) is an oomycete pathogen that causes downy mildew disease on Arabidopsis. This obligate biotroph manipulates the homeostasis of its host plant by secreting numerous effector proteins, among which are the RxLR effectors. Identifying the host targets of effectors and understanding how their manipulation facilitates colonization of plants are key to improve plant resistance to pathogens.
View Article and Find Full Text PDFS. aureus bacteremia with acute transverse myelitis case report: Utility of molecular techniques.
J Infect Chemother
September 2024
Article Synopsis
- A 60-year-old man experienced bacteremia and acute transverse myelitis (ATM) due to Staphylococcus aureus, presenting with symptoms like high fever, quadriplegia, and respiratory failure, without a clear source of infection.
- Bacterial ATM is rare and often difficult to diagnose, especially when caused by isolated infections in the spinal cord.
- The rapid diagnosis in this case resulted from teamwork among clinicians, infectious disease specialists, and microbiologists, along with advanced testing methods on cerebral spinal fluid (CSF).
Article Synopsis
- Dalbavancin is a long-acting antibiotic effective for treating acute bacterial skin infections, which helps address hospital bed shortages.
- During 2017-2023, strategies implemented in hospitals saved over 1,400 hospitalization days by efficiently managing patient admissions and discharges.
- The treatment showed a 99.5% success rate, with minimal minor side effects, making it a strong option for managing infections in resource-limited healthcare settings.
Staphylococcus aureus bacteremia presents clinical complexities, with prolonged duration associated with unfavorable outcomes. This research delves into unconventional treatments, such as combinations involving daptomycin, oxacillin, ceftaroline, and fosfomycin, with the aim of swiftly sterilizing bloodstream infection to reduce complications. Our examination of 30 MSSA bacteremia patients with infective endocarditis uncovers differing results between single-agent therapies (oxacillin or daptomycin) and combined treatment plans.
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